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As COVID-19 vaccinations begin across the U.S. and the new president soon be inaugurated, what can we expect from 2021? Walter Isaacson, a well-known author of bestselling biographies, is our first guest of the year. Recently he volunteered for the Pfizer/BioNTech clinical trial, where new technologies were used to develop a vaccine, innovations created by scientists he is writing about in his new book. We asked Mr . Isaacson what we can learn from our history and these scientific breakthroughs.